1、 主要发表的学术论文： 1. Li, Y. M.; Sun, Y. T.; Li, B. Y.; Qin, H. B*. Total Synthesis of Dysifragilone A、B and Dysidavarone Org. Lett. 2021, Accepted. 2. Zhang, D. W.; Fan, H. L; Zhang, W.; Li, C. J.; Luo, S.; Qin, H. B., Collective enantioselective total synthesis of (+)-sinensilactam A, (+)-lingzhilactone B and (-)-lingzhiol: divergent reactivity of styrene. Chem. Commun. 2020, 56, 10066-10069. 3. Ding, W. Y.; Yan, Y. M.; Meng, X. H.; Nafie, L. A.; Xu, T.; Dukor, R. K.; Qin, H. B.*; Cheng, Y. X.*, Isolation, Total Synthesis, and Absolute Configuration Determination of Renoprotective Dimeric N-Acetyldopamine-Adenine Hybrids from the Insect Aspongopus chinensis. Org. Lett. 2020, 22, 5726-5730. 4. Wang, Y. K.; Yang, X. N.; Zhu, X.; Xiao, X. R.; Yang, X. W.; Qin, H. B*.; Gonzalez, F. J.; Li, F. Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity. J Agric. Food Chem. 2019, 67, 8243-8252. 5. Zhang, D. W.; Xu, W. D.; Fan, H. L.; Liu, H. M.; Chen, D.; Liu, D. D.*; Qin, H. B*. Total Synthesis of (+/-)-Cochlearol A. Org. Lett. 2019, 6761-6764. 6. Wang, Y. K.; Yang, X. N.; Zhu, X.; Xiao, X. R.; Yang, X. W.; Qin, H. B.*; Gonzalez, F. J.; Li, F. Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity. J Agric. Food Chem. 2019, 67, 8243-8252. 7. He, H., Chen, D., Li, X., Li, C.-J., Zhao, J. H.,* and Qin, H. B. *, Synthesis of trisaccharide repeating unit of fucosylated chondroitin sulfate. Org. Biomol. Chem., 2019, 17, 2877-2882. 8. He, H.; Qin, H. B.* ZnBr2-catalyzed direct C-glycosylation of glycosyl acetates with terminal alkynes. Org. Chem. Front. 2018. 5, 1962-1966. 9. Liu, H.-M.; Chen, D.; Xu, W.-D.; Dang, L.-Z*.; Qin, H. B. * Total synthesis of (-)-akaol A via a conformational constraint strategy. Org. Chem. Front. 2018. 5, 1886-1889. 10. Xia, F.; Zhang, D.-W.; Wu, C.-Y.; Geng, H.-C.; Xu, W.-D.; Zhang, Y.; Yang, X.-W.; Qin, H. B. *; Xu, G*. Isolation, structural elucidation, and synthetic study of salviyunnanone A, an abietane derived diterpenoid with a 7/5/6/3 ring system from Salvia yunnanensis. Org. Chem. Front. 2018, 5, 1262-1266. 11. Li, C.-J.; Xia, F.; Wu, R.; Tan, H.-S.; Xu, H.-X*.; Xu, G.*; Qin, H. B. *. Synthesis and Cytotoxicities of Royleanone Derivatives. Nat. Prod. Bioprospect. 2018, 8, 453-456. 12. Li, C.-J.; Xia, F.; Zhang, W.; Wang, K.; Xu, G*.; Qin, H. B. *. Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives. Tetrahedron Lett. 2018, 59, 2607-2609. 13. Li, M. M.; Xia, F.; Li, C. J.; Xu, G.*; Qin, H. B.* Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives. Tetrahedron Lett. 2018, 59, 46-48. 14. Chen, D.; Xu, W.-d.; Liu, H.-M.; Li, M.-M.; Li, X.-N.; Yan, Y.-M.; Li, Y.; Cheng, Y.; Qin, H. B.,* Enantioselective total synthesis of (+)-Lingzhiol via tandem semipinacol rearrangement/Friedel-Crafts type cyclization. Chem. Commun. 2016, 52, 8561-8564. 15. 2. Chen, D.; Li, X.-M.; Liu, H.-M.; Li, M.-M.; Cheng, Y.-X.; Qin, H. B.,* Total synthesis of (±)-Lingzhilactone B via semipinacol rearrangement. Tetrahedron Lett. 2016, 57, 2877-2879. 16. Xu, W.-D.; Li, L.-Q.; Li, M.-M.; Geng, H.-C.; Qin, H. B.,* Catalytic Asymmetric Formal Total Synthesis of (−)-Triptophenolide and (+)-Triptolide. Nat. Prod. Bioprospect. 2016, 6, 183-186. 17. Yu, Q.-Y.; Zhong, H.-M.; Sun, W.-W.; Zhang, S.-J.; Cao, P.; Dong, X.-P.; Qin, H. B.; Liu, J.-K.; Wu, B., Palladium-Catalyzed C(sp3)−H Functionalization at the C3 Position of l-Pipecolinic Acid Derivatives. Asian J. Org. Chem. 2016, 5, 608-612. 18. Zhou, M.; Li, X.-R.; Tang, J.-W.; Liu, Y.; Li, X.-N.; Wu, B.; Qin, H.-B.; Du, X.; Li, L.-M.; Wang, W.-G.; Pu, J.-X.; Sun, H.-D., Scopariusicides, Novel Unsymmetrical Cyclobutanes: Structural Elucidation and Concise Synthesis by a Combination of Intermolecular [2 + 2] Cycloaddition and C-H Functionalization. Org. Lett. 2015, 17, 6062-6065. 19. Cheng, D.; Liu, H.; Li, M.; Yan, Y.; Xu, W.; Li, X.; Cheng, Y.; Qin, H.* A Concise Synthesis of (±)-Lingzhiol via epoxy-arene cyclization. Chem. Commu. 2015, 51, 14594-14596. 20. Zhao, L.; Wu, M.; Xiao, C.; Yang, L.; Zhou, L.; Gao, N.; Li, Z.; Chen, J.; Chen, J.; Liu, J*.; Qin, H*.; Zhao, J.*, Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan. Proc. Natl. Acad. Sci. 2015, 112, 8284-8289. 21. Yang, X. W.; Li, M. M.; Liu, X.; Ferreira, D.; Ding, Y.; Zhang, J. J.; Liao, Y.; Qin, H. B. *; Xu, G.*, Polycyclic Polyprenylated Acylphloroglucinol Congeners Possessing Diverse Structures from Hypericum henryi. J. Nat. Prod. 2015, 78, 885-895. 22. Li, X. Y.; Yang, Y. F.; Peng, X. R.; Li, M. M.; Li, L. Q.; Deng, X.; Qin, H. B. *; Liu, J. Q.; Qiu, M. H., One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B. Org. Lett. 2014, 16, 2196-2199. 五年前 23. Qin, H. B.; Yamagiwa, N.; Matsunaga, S.; Shibasaki, M., Bismuth-catalyzed direct substitution of the hydroxy group in alcohols with sulfonamides, carbamates, and carboxamides. Angew. Chem. Int. Edit. 2007, 46, 409-413. 24. Qin, H. B.; Yamagiwa, N.; Matsunaga, S.; Shibasaki, M., Bismuth-catalyzed intermolecular hydroamination of 1,3-dienes with carbarnates, sulfonamides, and carboxamides (vol 128, pg 1611, 2006). J. Am. Chem. Soc. 2006, 128, 4162-4162. 25. Yamagiwa, N.; Qin, H. B.; Matsunaga, S.; Shibasaki, M., Lewis acid-Lewis acid heterobimetallic cooperative catalysis: Mechanistic studies and application in enantioselective aza-Michael reaction. J. Am. Chem. Soc. 2005, 127, 13419-13427. 2 授权专利 光学活性灵芝酚中间体及其制备方法。发明人：秦红波，陈东，刘浩淼，许文丹 专利号：ZL 2016 1 0263852.9 授权公告号 CN 106117177 B |
