姓  名：

樊保敏

1.研究方向

[1] 21572198,无水碘化氢的制备及其与α，β-不饱和羰基化合物的不对称共轭加成反应研究，项目负责人，国家自然科学基金，65万，2016.01-2019.12。

[2] 21362043，端基炔烃对氧/氮杂苯并降冰片烯的不对称催化开环反应研究，项目负责人，国家自然科学基金，50万，2014.01-2017.12。

[3] 21162040，端基炔烃C-H键和冰片烯类化合物中C=C双键的不对称加成反应及其产物的抗癌活性，项目负责人，国家自然科学基金，55万，2012.01-2015.12。

[4] 20902080，不对称催化的[2+2]环化反应及其在斑蝥素类抗癌活性分子合成中的应用研究，项目负责人，国家自然科学基金，19万，2010.01-2012.12。

[5] 2017FA004，氮杂苯并降冰片烯与醇的不对称开环反应及其在神经活性药物中的应用研究，项目负责人，云南省应用基础研究计划重点项目，50万，2017.06-2020.05。

[6] 2012FB170，氧杂苯并冰片烯的不对称硅氢化反应及其在新型除草剂合成中的应用研究，项目负责人，云南省应用基础研究计划面上项目， 10万，2012.01-2015.12。

[7] ZD2015012，无水碘化氢溶液的制备及其在碘代有机化合物合成中的应用研究，项目负责人，云南省教育厅科学研究基金重大专项， 10万，2015.09-2017.08。

[8] 201505，路易斯酸共催化剂在过渡金属催化的氧/氮杂苯并冰片烯中的不对称开环反应研究，项目负责人，元素有机化学国家重点实验室开放基金项目，3万，   2015.12-2016.12。

[9] 201302，氧杂苯并降冰片烯与端基炔烃间的新型反应研究，项目负责人，元素有机化学国家重点实验室开放基金项目，3万，2013.12-2014.12。

[10] 201206 ，冰片烯类化合物不对称氢化炔基化反应中手性铑催化剂的开发研究，项目负责人，项目负责人，元素有机化学国家重点实验室开放基金项目，3万，2012.12-2013.12。

讲授本科生课程：有机化学、有机化学实验、药用有机化学实验、仪器分析实验、无机及分析化学

讲授研究生课程：金属有机化学、研究专题、色谱分析、有机化学专业英语及论文写作

[1] Ruhima Khan, Jingchao Chen, Baomin Fan*.Versatile Catalytic Reactions of Norbornadiene   Derivatives with Alkynes . Adv.Synth.Catal.   2020, DOI:10.1002/adsc.201901494 .

[2] Guangrui Shi,   Ruhima Khan, Xuexin Zhang, Yong Yang*, Yong Zhan, Juan Li, Yang Luo, Baomin Fan*. Rhodium-Catalyzed Direct   ortho C-H Thiolation of Cyclic N-Sulfonyl Ketimines.  Asian J. Org. Chem. 2020, DOI: 10.1002/ajoc.202000017.

[3] Keyang   Zhang, Ruhima Khan, Jingchao Chen, Xuexin Zhang, Yang   Gao, Yongyun Zhou*,  Kangkui Li, Youxian Tian, Baomin Fan*.  Directing-   Group-Controlled Ring-Opening Addition and Hydroarylation of   Oxa/azabenzonorbornadienes with Arenes via C–H Activation. Org.   Lett. 2020, 22, 3339-3344.

[4] Jiayan   Li,Ronibala Devi Laishram, Jingchao Chen*, Dandan Xu, Guangrui Shi,   Haiping Lv, Ruifeng Fan, Baomin Fan*.   Regioselective Hydroiodination of Alkynes by the in situ Generated HI. Asian J. Org. Chem. 2020, 9, 73 – 76.

[5] Kangkui Li, Xuexin Zhang, Jingchao Chen*, Yang   Gao, Chunhui Yang, Keyang Zhang, Yongyun Zhou, Baomin Fan*. Blue Light Induced Difluoroalkylation of   Alkynes and Alkenes . Org. Lett., 2019, 21,  9914-9918 .

[6] Xia Zhang, Jingchao Chen*, Ruhima Khan, Guoli Shen,   Zhenxiu He, Yongyun Zhou, Baomin Fan*,   Rhodium-Catalyzed Transfer Hydrogenation of Quinoxalines with Water as   Hydrogen Source.  Org. Biomol. Chem., 2019,   17, 10142–10147 .

[7] Yongyun Zhou, Ruhima   Khana, Baomin Fan*, Lijin Xu*, Ruthenium-Catalyzed Selective Reduction of Carboxylic Esters and Carboxamides. Synthesis. 2019, 51,   2491-2505.

[8] Jianxiao Ni, Jingchao   Chen, Yongyun Zhou*, Gaowei Wang, Sida Li, Zhenxiu He, Weiqing Sun, Baomin   Fan*. Rhodium-Catalyzed Asymmetric   [2+2+2] Cycloaddition Reactions of 1,6-Enynes and Oxabenzonorbornadienes. Adv.Synth. Catal., 2019. 361.   3543-3547.

[9] Yang Gao, Xuexin Zhang, Ronibala Devi   Laishram,Jingchao Chen*, Kangkui Li, Keyang Zhang, Guangzhi Zeng, Baomin Fan *. Cobalt-Catalyzed   Transfer Hydrogenation of α-Ketoesters and N-Cyclicsulfonylimides Using H₂O as   Hydrogen Source. Adv.Synth. Catal., 2019. 361. 3991-3997.

[10] Xuexin Zhang, Yang Gao, Jingchao Chen*, Ruifeng   Fan, Guangrui Shi, Zhenxiu He, Baomin   Fan*. Rh(III)-Catalyzed Ring-Opening Addition of Azabenzonorbornadienes   with Cyclic N-Sulfony Ketimines via C-H Bond Activation. Adv.Synth. Catal., 2019.   361,4495-4499 .

[11] Sida Li, Ruhima Khan, Xia Zhang, Yong Yang*,   Zheting Wang, Yong Zhan, Yuze Dai, Yue-e Liu, Baomin Fan* . One Stone Two Birds:   Cobalt Catalyzed in situ Generation of Isocyanate and Benzyl alcohol for the   Synthesis of N-aryl Carbamates. Org. Biomol. Chem., 2019, 17,   5891-5896 .

[12] Xuexin Zhang, Jingchao Chen,* Yang Gao, Kangkui   Li, Yongyun Zhou, Weiqing Sun, Baomin Fan* .Photocatalyzed Transfer Hydrogenation and   Deuteriation of Cyclic N-Sulfonylimines. Org. Chem. Front., 2019, 6, 2410-2414.

[13] Haiping Lv, Ronibala Devi Laishram, Jiayan Li,   Yongyun Zhou*, Dandan Xu, Sagar More,Yuze Dai, Baomin Fan*. Photocatalyzed Oxidative Dehydrogenation of   Hydrazobenzenes to Azobenzenes. Green Chem.,   2019, 21, 4055-4061.

[14] Kangkui Li, Ruhima Khan, Xuexin Zhang, Yang Gao, Yongyun   Zhou*, Heng Tan, Jingchao Chen, Baomin   Fan *. Cobalt catalyzed stereodivergent semi- Q2 hydrogenation of alkynes   using H₂O as the hydrogen source. Chem. Commun., 2019, 55, 5663—5666.

[15] Guoli Shen, Ruhima Khan*, Haiping Lv, Yong Yang,   Xia Zhang, Yong Zhan,Yongyun Zhou and   Baomin Fan*. Palladium/silver co-catalyzed syn-stereoselective asymmetric   ring-opening reactions of azabenzonorbornadienes with amides. Org. Chem. Front.,2019, 6, 1423–1427.

[16] Haiping Lv, Ronibala Devi Laishram, Jiayan Li,   Guangrui Shi, Weiqing Sun*, Jianbin Xu, Yong Yang,Yang Luo, Baomin Fan*. Nickel(0) catalyzed   oxidation of organosilanes to disiloxanes by air as an oxidant. Tetrahedron Letters.2019,60, 971–974.

[17] He Zhenxiu,Zhou Yongyun*,Sun,Weiqing,Fan   Ruifeng,Shen,Guoli,Fan Baomin*.   Asymmetric Ring Opening Reaction of Oxabenzonorbornadienes With Phenols   Promoted By Rhodium/Zinc Complexes. Chin.   J. Org. Chem., 2019, 39, 754-760.

[18] Guoli Shen, Jingchao Chen,* Dandan Xu, Xia Zhang,   Yongyun Zhou,and Baomin Fan*. Asymmetric   Transfer Hydrogenation of Heterobicyclic Alkenes with Water as Hydrogen   Source. Org. Lett.,2019, 21,   1364−1367.

[19] Xuexin Zhang, Yang Gao, Ronibala Devi Laishram,   Kangkui Li,Yong Yang*, Yong Zhan, Yang Luo,

Baomin Fan *. Pd(II)/Zn co-catalyzed chemo-selectivehydrogenation   ofα-methylene-γ-ketocarboxylic acids. Org. Biomol. Chem., 2019, 17, 2174–2181.

[20] Lingling Zou, Weiqing Sun*, Ruhima Khan, Haiping   Lv, Heng Tan, Jianbin Xu, Junlin Yin,  Baomin Fan*, Palladium Catalyzed   Tandem Reaction of Oxabenzonorbornadienes with Anhydrides, Eur. J. Org. Chem., 2019, 746–752.  

[21] GuoliShen,   Ruhima Khan, Fan Yang, Yong Yang,* DongdongPu, Yang Gao, Yong Zhan, Yang Luo Baomin Fan*. Pd/Zn Co-catalyzed   Asymmetric Ring-opening Reactions of Aza/Oxabicyclic alkenes with Oximes.Asian J. Org. Chem. 2019, 8, 97 -102.

[22] Chaoyuan Zeng, Guoli Shen, Fan Yang,   Jingchao Chen,* Xuexin Zhang, Cuiping Gu, Yongyun Zhou, Baomin Fan*. Rhodium-Catalyzed   Generation of Anhydrous Hydrogen Iodide: An Effective Method for the Preparation of   Iodoalkanes. Org. Lett., 2018, 20, 6859-6862.

[23] Yang Gao, Yang Fan, Dongdong Pu, Ronibala Devi   Laishram*, Ruifeng Fan, Guoli Shen, Xuexin Zhang, Jingchao Chen, Baomin Fan*. Pd/Zn(OTf)₂ Co‐catalyzed Asymmetric   Hydrogenation of Imines under Normal Pressure of Hydrogen. Eur.J. Org.Chem., 2018, 45, 6274-6279.

[24] Dongdong Pu, Yongyun Zhou,*   Fan Yang,Guoli Shen,Yang Gao, Weiqing Sun,Ruhima Khan and Baomin Fan*.Asymmetric ring-opening   reactions ofazabenzonorbornadienes through transfer

hydrogenation using secondary amines ashydrogen   sources: tuning of absoluteconfiguration by acids.Org. Chem. Front., 2018, 5, 3077-3082.

[25] Dapeng Zhang, Ruhima Khan,* Fan Yang, Xuexin   Zhang, Guoli Shen, Yang Gao, Ruifeng Fan, Weiqing Sun, and Baomin Fan*.Palladium and Lewis acid Co-catalyzed Reductive Asymmetric Ring-Opening   Reaction of Azabenzonorbornadienes with TertiaryAmines as Hydrogen Source. Eur. J. Org. Chem. 2018, 26,   3464–3470.

[26] Hongyu Qin, Jingchao   Chen,* Kangkui Li, Zhenxiu He, Yongyun Zhou, Baomin Fan*. Nickel-Catalyzed   Asymmetric [2+2] Cycloaddition Reaction ofHetero-Bicyclic Alkenes   with Internal Alkynes.Chem. Asian J. 2018, 13, 2431-2434.

[27] Jirong   Hu,JianbinXu*,LinglingaZou,HaipingLv,Ruifeng Fan, Na Liu, Yongyun Zhou, Baomin Fan*.Rhodium Catalyzed   Asymmetric Ring-Opening Reaction of OxabenzonorbornadieneswithAnhydride. Chin. J. Org. Chem., 2018, 38, 1687-1694.

[28] Zhenxiu He, Yongyun Zhou*,   Baiqiu Han, XinXu, Yun Li, HongyuQin,Ruifeng Fan, Ronibala Devi Laishram, Baomin Fan*. Asymmetric ring-opening   reaction of azabenzonorbornadienes with phenols promoted by   palladium/(R,R)-DIOP complex. Tetrahedron,   2018, 74, 2174-2181.

[29] Fan Yang, Jingchao Chen*,   GuoliShen, Xuexin Zhang, Baomin Fan*.   Asymmetric Transfer Hydrogenation Reactions of N-Sulfonylimines by Using   Alcohols as Hydrogen Sources. Chem.Comm.,   2018, 54, 4963-4966.

[30] Jingchao Chen,*   Lingling Zou, ChaoyuanZeng, Yongyun Zhou, Baomin Fan*. Rhodium-Catalyzed Asymmetric ArylativeRing-Opening   Reactions ofHeterobicyclic Alkenes with Anilines. Org. Lett., 2018, 20, 1283−1286.

[31] Yongyun Zhou, Lu Yu,Jingchao   Chen, Jianbin Xu, Zhenxiu He, Guoli Shen, and Baomin Fan*. Rhodium-Catalyzed Asymmetric Cyclization/Addition   Reactions of 1,6-Enynes and Oxa/Azabenzonorbornadienes. Org. Lett., 2018, 20, 1291−1294.

[32] Yun Li, Jingchao Chen,*   Zhenxiu He, Hongyu Qin, Yongyun Zhou, Ruhima Khan, Baomin Fan*.Cobalt-catalyzed asymmetric reactions of heterobicyclic   alkenes with in situ generated organozinc halides. Org. Chem. Front., 2018,   5, 1108-1112.

[33] Jingchao Chen, Xin Xu,*   Zhenxiu He, Hongyu Qin, Weiqing Sun, Baomin   Fan*. Nickel/Zinc Iodide Co-catalytic Asymmetric [2+2] Cycloaddition   Reactions of Azabenzonorbornadienes with Terminal Alkynes. Adv. Synth. Catal., 2018, 3, 427-431.

[34] Fujie Ma, Jingchao Chen,*   Fan Yang, Madhuri Vikas Shinde, Yongyun Zhou, Baomin Fan*. Palladium/Zinc Co-catalyzed Asymmetric Transfer   Hydrogenation of Oxabenzonorbornadienes with Alcohols as Hydrogen Sources. Org. Biomol. Chem., 2017, 15, 2359-2362.

[35] Meina Zhu, Jingchao Chen,*   Xiaobo He, Cuiping Gu, Jianbin Xu, Baomin   Fan*. Iridium-Catalyzed Anti-Stereoselective Asymmetric Ring Opening   Reactions of Azabenzonorbornadienes with Carboxylic Acids. J. Org. Chem., 2017, 82, 3167-3172.

[36] Wei Zhang, Jingchao   Chen,*Guangzhi Zeng, Fan Yang, Jianbin Xu, Weiqing Sun, Madhuri Vikas hinde, Baomin Fan*. Asymmetric Ring-Opening   Reactions of Aza- and Oxa-bicyclic Alkenes with Boronic Acids Using a   Palladium/Zinc Co-catalytic System. J.   Org. Chem., 2017, 82, 2641-2647.

[37] Xiaobo He, Jingchao Chen*, Xin Xu, Fan Yang, Cuiping Gu, Yongyun Zhou, Baomin Fan*. Rhodium/zinc   co-catalyzed asymmetric ring opening reactions of oxabenzonorbornadienes with   carboxylic acids.  Tetrahedron: Asymmetry, 2017,   28, 62-68.

[38] Fan Yang, Jingchao Chen   ,Jianbin Xu, Fujie Ma, Yongyun Zhou, Madhuri Vikas Shinde, Baomin Fan*. Palladium/Lewis Acid   Co-catalyzed Divergent Asymmetric Ring-Opening Reactions of   Azabenzonorbornadienes with Alcohols. Org.   Lett., 2016, 18, 4832-4835.

[39] Yongyun Zhou, Cuiping Gu,   Jingchao Chen, Meina Zhu, Fan Yang, Jianbin Xu, and Baomin Fan*. Enantioselective Ring Opening Reactions of   Azabenzonorbornadienes with Carboxylic Acids. Adv. Synth. Catal., 2016,   358, 3167-3172.

[40] Qingjing Yang,   Pui Ying Choy, Yinuo Wu,* Baomin Fan* and   Fuk Yee Kwong*. Oxidative coupling between C(sp2)–H andC(sp3)–H bonds of   indoles and cyclic ethers/cycloalkanes. Org.   Biomol. Chem., 2016, 14, 2608-2612.

[41] Xin Xu, Jingchao Chen,   Zhenxiu He, Yongyun Zhou and Baomin   Fan*. Rhodium-catalyzed a symmetric ring openingreaction of   oxabenzonorbornadienes with amines using ZnI₂ as the activator. Org. Biomol. Chem., 2016, 14, 2480-2486.

[42] Yongyun Zhou, Zhiwu   Lu, Baiqiu Han, Chaoyuan Zeng, Zhenhua Zhang, Baomin Fan*. Iridium-catalyzed highly enantioselective ring   opening reaction of oxabenzonorbornadienes with amines. Tetrahedron: Asymmetry, 2015,   26, 1354-1359.

[43] Zhiwu Lu, Jun Wang,*   Baiqiu Han, Sifeng Li, Yongyun Zhou, Baomin   Fan*. Palladium-Catalyzed

Asymmetric Ring Opening Reaction of Azabenzonorbornadienes with Aromatic   Amines. Adv. Synth. Catal. ,2015, 357, 3121 -3125.

[44] Chaoyuan Zeng, Fan Yang,   Jingchao Chen, Jun Wang,* Baomin Fan*.   Iridium/Copper-Cocatalyzed Asymmetric Ring Opening Reaction of Azabenzonorbornadienes   with Amines. Org. Biomol. Chem., 2015, 13, 8425-8428.

[45] Jingchao Chen,   Shanshan Liu, Yongyun Zhou, Sifeng Li, Chengyuan Lin, Zhaoxiang Bian, Baomin Fan*. Palladium/Silver Cocatalyzed   Tandem Reactions of Oxabenzonorbornadienes with Substituted Arylacetylenes: A   Simple Method for the Preparation of 1,2-Diarylethanones and   1,2-Diarylacetylenes. Organometallics, 2015, 34, 4318-4322.

[45] Yongyun Zhou, Shanshan Liu,   Hualei Chen, Jingchao Chen, Weiqing Sun, Sifeng Li, Qingjing Yang, Baomin Fan*. AgOTf-Catalyzed Tandem   Reaction of Oxabenzonorbornadienes With Arylacetylenes. Chin. J. Chem.,2015, 33, 1115-1118.

[46] Qingjing Yang, Yongyun Zhou,   Jingchao Chen, Xiaobo He, Jianbin Xu, Fuk Yee Kwong, Baomin Fan*. Pd-Catalyzed Allylic Alkynylation of Allylic   Acetates with Terminal Alkynes. Eur. J.   Org. Chem., 2015, 5330-5333.

[47] Qingjing Yang,   Puiying Choy, Baomin Fan,* and   Fukyee Kwong*. Enantioselective Hydroalkynylation of Non-Polar Carbon-Carbon Double   Bonds: Iridium-Catalyzed Asymmetric Addition Reaction of Terminal Alkyne C-H   Bonds to Substituted Norbornadienes. Adv.   Synth. Catal., 2015, 357, 2345 -2350.

[48] Sifeng Li, Jianbin Xu, Baomin Fan,* Zhiwu Lu, Chaoyuan Zeng,   Zhaoxiang Bian, Yongyun Zhou, and Jun Wang*. Palladium/Zinc Co-Catalyzed   syn-StereoselectivelyAsymmetricRing-Opening Reaction of   Oxabenzonorbornadienes with Phenols. Chem.   Eur. J., 2015, 21, 9003 -9007.

授权专利:

[1] Zhaoxiang Bian, Baomin Fan, Chengyuan Lin, Yongyun   Zhou, Jingchao Chen. Method for The Preparation of Iodoalkanes. 2018.08.07.   USA. US10040740B2.

[2] Zhaoxiang   Bian, Chengyuan Lin, Huaixue Mu, Baomin   Fan, Yongyun Zhou, Jingchao Chen, Aiping Lu, Albert Sun-Chi Chan.   Palladium/Silver Co-Catalyzed Tandem Reactions Syntheis of   Phenylacetophenone  Derivatives by Oxabenzonorborn   Adienes and Their Anti-tumor or Anti-cancer Activities. 2017.10.10. USA.   US9783519B2.

[3]   Zhaoxiang Bian, Chengyuan Lin, Baomin   Fan, Huaixue Mu, Yongyun Zhou, Weimin Zeng, Aiping Lu, Albert Sun-Chi   Chan. Oxanorbornadiene Derivatives and Their Anticancer Activities.   2015.09.01. USA. US9120816B2.

[4] Albert   Sun-Chi Chan, Baomin Fan, Jun   Wang, Chengyuan Lin, Chao Huang, Qingjing Yang, Jianbin Xu, Zhaoxiang Bian,   Aiping Lu, Jun Hu. Asymmetric Synthesis of Norcantharidin Analogues by   Alkynylation of Oxabenzonorbornadienes and Their Anticancer Activities.   2014.09.16. USA. US8835658B2.

[5]樊保敏, 徐歆, 周永云, 陈景超.一种新型化合物及其制备方法和应用. 2019.03.15.CN.ZL201510740517.9

申请专利：

1、樊保敏，陈景超，周永云，曾广智，尹俊林，林成源，孙蔚青， 一种铑催化制备碘代烷烃方法. 2017.11.14.201711122416.0

2、樊保敏，陈景超，周永云，曾广智，尹俊林，林成源，孙蔚青，一种铑催化制备碘代烷烃方法，    201711122416.0 

3、樊保敏、陈景超、樊瑞峰、周永云、孙蔚青、尹俊林，一种高效制备碘化苄及其衍生物的方法，201711420291.X  

4、樊保敏，陈景超，周永云，樊瑞峰，孙蔚青，曾广智，尹俊林，林成源，郝朝威，一种特异性检测铜离子和硫离子的多肽、化学荧光传感器及其制备方法与应用，201811048532.7  

5、樊保敏，陈景超，周永云，樊瑞峰，孙蔚青，曾广智，尹俊林，林成源，吕海平，一种硅醇类有机化合物及制备方法，201910176111.0

6、樊保敏、周永云、陈景超、曾广智、尹俊林、徐丽娟、李瑞涛，一种凤尾茶天然凉茶饮料及其制备方法，201910291387.3   

7、樊保敏，陈景超，周永云，樊瑞峰，孙蔚青，林成源，吕海平，一种芳香偶氮苯类有机化合物的制备方法，201910827116.5 

8、樊保敏，杨大坚，詹永，罗杨，李娟，陈景超，周永云，沈国礼，一种制备手性氨基酸酯和手性氘代氨基酸酯的方法，201911225569.7   

9、樊保敏，陈景超，周永云，和振秀，樊瑞峰，孙蔚青，沈国礼，一种以重水为制备氘代氨基酸酯的方法，2019112975912 

2015.02 特聘教授

2016.01 云南省中青年学术和技术带头人

2019.02   云南省万人计划青年拔尖人才

2019.05   云南省自然科学三等奖