姓名： 何永辉

学历： 博士研究生

职务： 副院长

办公电话：0871-65926040

通信地址： 云南民族大学呈贡校区民族医药学院

职称： 副教授

学位： 博士

电子邮箱：hee_csu@126.com

邮编： 650504

2007年-2012年，中南大学应用化学专业 博士

2004年-2007年，中南大学生物化工专业 硕士

2000年-2004年，中南大学制药工程专业 本科

研究方向：药物合成方法学，有机电化学合成

招生专业:药学、化学生物学

1、抗肿瘤耐药类天然产物抑制剂的理性设计、合成及生物活性研究，云南省"兴滇英才支持计划"青年人才专项项目， 2023年1月-2027年12月，75万元；

2、电催化合成含氮杂环化合物的新方法学研究，云南省自然科学基金面上项目，2021.1-2024.12，项目批准号：202101AT070079,10万元；

3、2、基于Rictor靶标的计算机辅助药物分子设计，国家自然科学基金理论物理专项，2016.1-2016.12，项目批准号：11547233，5万元；

4、基于靶点Rictor的靶向抗肿瘤血管新生药物的研究，云南省自然科学基金面上项目，2016.10-2019.9，项目批准号：2016FB149，10万元。

化工原理、药物合成反应

[1] Ying Gao, Mingxu Wang, Jingxian Sun, Xiao-Jing Zhao*,Yonghui He*, Electrochemical-induced solvent-tuned selective C(sp3)-H bond activation towards the synthesis of C3-functionalized chromone derivatives.Chemical Communications2024,60, 5050-5053.

[2] Mingxu Wang, Ying Gao, Xiao-Jing Zhao,Lu Gao*,Yonghui He*, Electrochemical multicomponent [2+2+1] cascade cyclization of enaminones and primary amines towards the synthesis of 4-acylimidazoles.Chemical Communications2024,60, 2677-2680.

[3] Zhi-Min Zong, Mingxu Wang,Xiao-Jing Zhao*,Yonghui He*, Bromide-catalyzed oxo-amination of alkenes towards the synthesis of α-amine ketones under photoelectrocatalysis conditions.Organic Chemistry Frontiers2024,11, 3525-3530.

[4] Zhi-Min Zong, Lizhu Zhang, Gan-Peng Li, Wei Wang,Xiao-Jing Zhao*,Yonghui He*, Electrochemical-Induced C–N Bond Formation: A New Method to Synthesis (Z)-Quinazolinone Oximes Using Primary Amines and Quinazolin-4(3H)-one.Organic Letters2024,26, 1271-1276.

[5] Kaixin Yang,Huaijun Tang*, Yuxiang Jiao, Long Gao, Meifang Zhang, Jing Qin, Wenyao Li, Shiyou Lu,Yonghui He*, An AIE-active orange-emitting cationic iridium(III) complex for latent fingerprints detection via a simple powder dusting method.Journal of Luminescence2023,257, 119721.

[6] Junying Zhang, Xiaojing Zhao,Ganpeng Li*,Yonghui He*, Electrochemical Synthesis of Masked Organoboronic Acids RB(dan) at Room Temperature.Chinese Journal of Organic Chemistry2023,43, 1815-1823.

[7]Yonghui He, Liang Zeng, Ming Li, Lijun Gu*, ShengyongZhang, Ganpeng Li*, Electrochemical Oxidative C-C Bond Cleavage of Ketones for C-N Bond Formation: A Route to Amides.The Journal of Organic Chemistry2022,87, 12622-12631.

[8] Yangli Wang, Xiao-Jing Zhao, Xi Wu, Lizhu Zhang,Ganpeng Li*,Yonghui He*, Electrochemical Synthesis of Trisubstituted Oxazoles and Imines from beta-Diketones and Amines.Chemelectrochem2022,9, e202200378.

[9] Xi Wu, Xiao-Jing Zhao, Lizhu Zhang,Ganpeng Li*,Yonghui He*, Electrooxidative Dehydrogenative Coupling of 1,4-Naphthoquinones with Amines: Facile Access to 2-Amino-1,4-naphthoquinones.Tetrahedron Letters2022,154208.

[10] Dongwen Zeng, Lizhu Zhang, Wei Wang, Ganpeng Li,Xiao-Jing Zhao*,Yonghui He*, Electrochemical Synthesis of Azaborininones under Metal-Catalyst-Free Mild Conditions.European Journal of Organic Chemistry2022,2022,

[11] Dongwen Zeng, Lijun Gu, Lizhu Zhang,Ganpeng Li*,Yonghui He*, Synthesis of aziridines by electrochemical oxidative annulation of chalcones with primary amines.Tetrahedron Letters2021,87, 153413.

[12] Yaqin Zhou, Zhiheng Zhao, Liang Zeng, Ming Li,Yonghui He*, Lijun Gu*, Recent Advance in Organic Electrochemical Synthesis of Nitrogenous Heterocyclic Compounds Involving Haloids as Mediators.有机化学2021,41, 1072-1080.

[13] Liang Zeng, Jing Li, Jun Gao, Xunhai Huang, Wei Wang, Xiaohui Zheng, Lijun Gu*, Ganpeng Li, Shengyong Zhang,Yonghui He*, An electrochemical oxidative multicomponent cascade annulation of ketones and amines used to produce imidazoles.Green Chemistry2020,22, 3416-3420.