基本情况

姓名：朱怡颖

职称：讲师

学历：博士研究生

学位：博士

电子邮箱：zyy1@ymu.edu.cn

通信地址：云南民族大学呈贡校区民族医药学院（邮编：650504）

教育经历

2014.09—2018.06 中国药科大学 中药学专业 学士

2018.09—2021.06 云南大学（与中国科学院昆明植物研究所联合培养）生物工程专业 硕士

2022.08—2025.07 香港中文大学 中医药学专业 博士

工作经历

2025.12—至今 云南民族大学民族医药学院 讲师

2021.07—2022.06 云南大学 李艳研究员课题组 科研助理

研究方向

天然产物抗肿瘤活性评价与作用机制研究。围绕中药与民族药来源的活性成分，开展抗肿瘤活性筛选、作用靶点确证及信号通路机制研究。

代表性论文

以第一作者或共同第一作者在 Phytomedicine、Science China Chemistry、Biochemical and Biophysical Research Communications 等期刊发表 SCI 论文 3 篇，另参与发表 SCI 论文 1 篇。

1. Yiying Zhu^#, Xiaoli Li^#, Grace Gar-Lee Yue, Julia Kin-Ming Lee, Si Gao, Mengru Wang, Chun Kwok Wong, Wei-Lie Xiao^*, Clara Bik-San Lau^*. Broussoflavonol F exhibited anti-proliferative and anti-angiogenesis effects in colon cancer via modulation of the HER2-RAS-MEK-ERK pathway. Phytomedicine, 2024, 135: 156243.

2. Xiao-Zheng Su^#, Yi-Ying Zhu^#, Jian-Wei Tang, Kun Hu, Xiao-Nian Li, Han-Dong Sun, Yan Li^*, Pema-Tenzin Puno^*. Pestaloamides A and B, two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp. HS30. Science China Chemistry, 2020, 63(9): 1208-1213.

3. Yiying Zhu^#, Zhangxun Zhao^#, Minggao Xue, Dan Wang, Guifeng Su, Xiaoman Ju, Qihong Yang, Shaohua Zhang, Dongmei Fan, Huifang Zhu, Min Yu, Yan Li, Lingmei Kong^*, Hongyu Zhou^*. Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway. Biochemical and Biophysical Research Communications, 2023, 659: 10-19.

4. Bicheng Cai, Liang Gong, Yiying Zhu, Lingmei Kong, Xiaoman Ju, Xue Li, Xiaodong Yang, Hongyu Zhou^*, Yan Li^*. Identification of Gossypol Acetate as an Autophagy Modulator with Potent Anti-tumor Effect against Cancer Cells. Journal of Agricultural and Food Chemistry, 2022, 70(8): 2589-2599.

注：#共同第一作者；*通讯作者。

获奖与荣誉

1. 获第十二届 GP-TCM 研究协会年会 Peter Hylands 奖

2. 获第二十届国际中医药研究生研讨会李时珍青年优秀论文奖

3. 获香港中文大学中医学院研究生研讨会 Best Investigator 奖

4. 获 2018 年云南大学硕士研究生三等奖学金

5. 获 2015 年中国药科大学三等奖学金

6. 获 2015 年中国药科大学“三好学生”称号

学术会议

1. Yiying Zhu, Grace Gar-Lee Yue, Chun Kwok Wong, Pema-Tenzin Puno, Clara Bik-San Lau. Investigation on the anti-tumor effects and underlying mechanism of Eriocalyxin B derivative compound 38 in colon cancer cells. 19th Meeting of the Consortium for the Globalization of Chinese Medicine, 2023, 口头报告, 中国成都.

2. Yiying Zhu, Grace Gar-Lee Yue, Chun Kwok Wong, Wei-Lie Xiao, Clara Bik-San Lau. Preclinical study on the anti-proliferative effects and underlying mechanisms of Broussoflavonol F in colon cancer. International Congress on Natural Products Research, 2024, 墙报, 波兰克拉科夫.

3. Yiying Zhu, Grace Gar-Lee Yue, Chun Kwok Wong, Wei-Lie Xiao, Clara Bik-San Lau. Preclinical study on the anti-proliferative, anti-metastatic effects of Broussoflavonol F and its underlying mechanisms in colon cancer. 20th International Postgraduate Symposium on Chinese Medicine, 2024, 口头报告, 中国香港.

4. Yiying Zhu, Grace Gar-Lee Yue, Chun Kwok Wong, Pema-Tenzin Puno, Clara Bik-San Lau. Investigation on the anti-metastatic effects of Eriocalyxin B derivative compound 38S in colon cancer. 12th Annual Meeting of the GP-TCM Research Association, 2024, 口头报告, 中国澳门.