何泽元，讲师，博士毕业于兰州大学生物化学与分子生物学专业，主要研究方向为多肽修饰策略研究，相关研究成果在Sci. Adv.，Chem. Sci.，Org. Lett.，Nat. Commun., Angew. Chem. Int. Ed.等SCI期刊发表学术论文10余篇，其中第一（含共同一作）作者3篇。
邮箱：hezy@ymu.edu.cn
代表性研究论文：
1.He, Z.; Zhao X.; Gao, W.-Y.; Bao, G.; Li, Y.; Zuo, Q.; Song, X.; Mou, L.-Y.; Sun, W.*; Wang, R., Controlled reversible methionine-selective sulfimidation of peptides. Sci. Adv. 2025, 11, eadv8712.
2.He, Z.; Liu, Y.; Bao, G.; Li, Y.; Zhao, X.; Zuo, Q.; Li, K.; Sun, W.*; Wang, R., Intermolecular sulfur atom transfer cascade enabled late-stage introduction of sulfilimines into peptides. Chem. Sci. 2024, 15, 17058-17063.
3.Liu, Y.; He, Z.; Ma, W.; Bao, G.; Li, Y.; Yu, C.; Li, J.; E, R.; Xu, Z.*; Wang, R.*; Sun, W.*, Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site. Org. Lett. 2022, 24, 9248-9253. (共同第一作者)
4.Zuo, Q.; Song, X.; Yan, J.; Bao, G.; Li, Y.; Shen, J.; He, Z.; Hu, K.*; Sun, W.*; Wang, R.*, Triazination/IEDDA Cascade Modular Strategy Installing Pyridines/Pyrimidines onto Tyrosine Enables Peptide Screening and Optimization. J. Am. Chem. Soc. 2025, 147, 9576-9589.
5.Bao, G.; Song, X.; Li, Y.; He, Z.; Zuo, Q.; E, R.; Yu, T.; Li, K.; Xie, J.*; Sun, W.*; Wang, R.*, Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts. Nat. Commun. 2024, 15, 6909.
6.Zuo, Q.; Li, Y.; Lai, X.; Bao, G.; Chen, L.; He, Z.; Song, X.; E, R.; Wang, P.; Shi, Y.; Luo, H.; Sun, W.*; Wang, R.*, Cysteine-Specific Multifaceted Bioconjugation of Peptides and Proteins Using 5-Substituted 1,2,3-Triazines. Adv. Sci. 2024, 11, 2308491.
7.Bao, G.; Wang, P.; Guo, X.; Li, Y.; He, Z.; Song, X.; E, R.; Yu, T.; Xie, J.*; Sun, W.*, Visible-light mediated deoxygenation of carboxylic acid for late-stage peptide modification targeting dehydroalanine. Org. Lett. 2023, 25, 8338-8343.
8.Yang, J.; He, Z.; Hong, L.; Sun, W.*; Wang, R.*, Asymmetric N-aminoalkylation of 3-substituted indoles by N-protected N, O-acetals: an access to chiral propargyl aminals. Org. Biomol. Chem. 2020, 18, 4169-4173.
9.Yang, J.; Wang, Z.; He, Z.; Li, G.; Hong, L.; Sun, W.*; Wang, R.*, Organocatalytic enantioselective synthesis of tetrasubstituted α-amino allenoates by dearomative γ-addition of 2,3-disubstituted indoles to β,γ-alkynyl-α-imino esters. Angew. Chem. Int. Ed. 2020, 59, 642-647.
10.Yang, J.; Sun, W.*; He, Z.; Yu, C.; Bao, G.; Li, Y.; Liu, Y.; Hong, L.*; Wang, R.*, Access to α, γ-diamino diacid derivatives via organocatalytic asymmetric 1,4-addition of azlactones and dehydroalanines. Org. Lett. 2018, 20, 7080-7084.
